Blood transfusions and human recombinant erythropoietin in premature newborn infants.

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Blood transfusions and human recombinant erythropoietin in premature newborn infants.

Transfusion with concentrated erythrocytes is a common form of treatment in many very premature infants. It is estimated that over 80% of infants requiring intensive care have received at least one blood transfusion as part of their treatment, and 37% more than two.' Frequent blood transfusions expose the infants to multiple donors. One survey reported that infants who were given more than one ...

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Recombinant erythropoietin therapy as an alternative to blood transfusions in infants with hereditary spherocytosis.

INTRODUCTION In hereditary spherocytosis, erythropoiesis has been described as 'sluggish' during the first months of life. The lack of appropriate erythropoietic response to compensate for increased red cell destruction necessitates blood transfusions in 70-80% of hereditary spherocytosis-affected infants during their first year of life. After this period, less than 30% require regular transfus...

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Cord Blood Lipid Profile in Premature, Near-Term and Term Newborn Infants

Introduction: The fetus needs a considerable amount of cholesterol for the development of tissues and organs.  Studies have suggested that genetic and environmental factors influence the composition of cord blood lipoproteins.  In this study, we aim to assess the effect of gestational age, sex and birth weight on the cord blood lipoproteins. Methods: We collected umbilical cord blood samples fr...

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RECOMBINANT ERYTHROPOIETIN AND BLOOD TRANSFUSION IN VERY LOW BIRTH WEIGHT INFANTS

 ABSTRACT Background: Very low birth weight infants ( <1500 g) frequently require blood transfusions because of repeated blood sampling accompanied by anemia of prematurity. Methods: In an attempt to identify the effect of human recombinant erythropoietin to decrease the requirement for blood transfusions, erythropoietin was administered to 24 pre term infants less than 1500 g prospectively fro...

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Red blood cell transfusions in newborn infants: Revised guidelines.

In general, health care professionals taking care of high risk infants in neonatal intensive care units have become more restrictive in their use of red blood cell transfusion over the past 10 years. The present statement is intended for those caring for high risk newborn infants (preterm to one month of age). The objectives of this statement are to provide guidelines to reduce the incidence of...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood - Fetal and Neonatal Edition

سال: 1996

ISSN: 1359-2998,1468-2052

DOI: 10.1136/fn.75.1.f65